MDI (Non-Isomer-Specific)CAS 26447-40-5
The CAS number commonly listed on SDSes for technical-grade MDI without isomer characterization.
Other Isocyanates substances:Toluene DiisocyanatePure MDIPolymeric MDI4,4'-MDI Homopolymer2,4'-MDIHexamethylene DiisocyanatePolymeric TDI
MDI belongs to the Isocyanates family — products shown above commonly contain one or more substances from this family
Toxic Chemical Databases
Substance-specific listings — these flags are for MDI alone, not for the broader family.
LBC Red List
Listed
Prop 65
Not Listed
IARC
Listed
NTP RoC
Listed
GSPI
Not Listed
REACH SVHC
Listed
TSCA
Listed
Chemical Type
Technical MDI Mixture
Chemical Description
Many SDS documents list MDI under this non-isomer-specific CAS rather than calling out 4,4'-MDI or 2,4'-MDI individually. The chemistry behaves as a representative mix of the MDI family. Regulatory listings (LBC Red List, IARC, NTP, REACH SVHC) capture this CAS to cover technical-grade products of unspecified isomer ratio.
Biological Activity
Severity scores specific to this substance, NOT the parent family average. Differences between siblings are real and meaningful.
Respiratory
10/10
Immune
9/10
Skin
8/10
Cancer
4/10
Reproductive
5/10
Developmental
5/10
Liver/Kidney
5/10
Neurological
4/10
Endocrine
3/10
Cardiovascular
3/10
Top Health Consequences
- Respiratory sensitization and occupational asthma
- Skin sensitization
- Same MDI-family hazard envelope
Pathways of Exposure
- Inhalation of aerosolized A-side during spray application
- Off-gassing from cured products with residual monomer
- Skin contact with uncured product
Building Materials with MDI
Listed alphabetically — product categories where this specific substance appears.
Polyurethane Adhesives & Sealants
Spray Polyurethane Foam
Two-Part Industrial Coatings
Want to screen a specific product? Drop the manufacturer's SDS into our SDS Toxic Chemical Screener — it screens this substance (CAS 26447-40-5) against all seven databases shown above.