Kidney damage, bone demineralization, and lung cancer — accumulates in the kidney with a 30-year half-life.

Substance-specific listings — these flags are for Cadmium alone, not for the broader family.
Cadmium accumulates in the renal cortex over decades — the human biological half-life is roughly 30 years. Once kidney cadmium burden exceeds ~200 µg/g cortex, kidney tubular damage begins; secondary effects include skeletal demineralization (the Japanese itai-itai disease). IARC Group 1 carcinogen for lung cancer. Construction sources include red and yellow cadmium pigments in pre-2000 PVC stabilizer formulations, cadmium plating on hardware, and cadmium-containing solder.
Severity scores specific to this substance, NOT the parent family average. Differences between siblings are real and meaningful.
Listed alphabetically — product categories where this specific substance appears.